Functional ultrasound (fUS) is an emerging neuroimaging modality that indirectly measures neural activity by detecting fluctuations in local blood dynamics. fUS acquisitions typically rely on the use of a 1D array transducer, which records hemodynamic activity in a single plane. A new technique named swept-3D fUS imaging obtains a full 3D volume of the brain by continuously moving a 1D array back-and-forth over the volume of interest. The standard procedure in fUS imaging involves filtering and averaging a number of ultrasound frames obtained at a single location to compute power-Doppler images, yet, in case of swept-3D fUS, the location of the recorded slice shifts at each time instant due to probe motion. In this work, we aim at discovering task-relevant components from 3D fUS data while taking into account the spatiotemporal differences in adjacent slices. We propose an alternating optimization scheme with general liner model-based regularization, and validate our method on swept-3D fUS data by identifying active regions and time traces within the mouse brain during a visual experiment.
|Title of host publication||ICASSPW 2023 - 2023 IEEE International Conference on Acoustics, Speech and Signal Processing Workshops, Proceedings|
|Publisher||Institute of Electrical and Electronics Engineers (IEEE)|
|Number of pages||5|
|Publication status||Published - 2023|
|Event||2023 IEEE International Conference on Acoustics, Speech and Signal Processing Workshops, ICASSPW 2023 - Rhodes Island, Greece|
Duration: 4 Jun 2023 → 10 Jun 2023
|Name||ICASSPW 2023 - 2023 IEEE International Conference on Acoustics, Speech and Signal Processing Workshops, Proceedings|
|Conference||2023 IEEE International Conference on Acoustics, Speech and Signal Processing Workshops, ICASSPW 2023|
|Period||4/06/23 → 10/06/23|
Bibliographical noteGreen Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.
- 3D functional ultrasound
- regularized factorization