Light intensity matching between different intravascular optical coherence tomography systems

Shengnan Liu, Jeroen Eggermont, Shimpei Nakatani, Boudewijn Lelieveldt, J Dijkstra

Research output: Chapter in Book/Conference proceedings/Edited volumeConference contributionScientificpeer-review

2 Citations (Scopus)


Currently two commercial intravascular optical coherence tomography (IVOCT) systems are available: Illumien Optis from St. Jude Medical (SJM) and Lunawave from Terumo. Both systems store the light intensity data in a raw vendor specic polar format. However, whereas SJM uses 16-bits per pixel Terumo uses 8-bits meaning the intensity values are in dierent ranges. This complicates quantitative light intensity based analysis when comparing results based on data from both systems. Therefore, this work aims to find an intensity transformation function from Terumo's 8-bit OFDI data to SJM's 16-bit range. The data consists of 8 pullbacks, 4 acquired with each system in the same arteries of 2 dierent patents pre- and post-stenting implantation. A total of 133 matching sections without stent struts from the two sets of pullbacks were identied based on landmarks such as side-branches and calcied regions. Since the main region of interest in the image is the tissue region only the pixels within 2mm behind the lumen border are used. In order to match the SJM data range, the Terumo data
was rescaled and cumulative distribution functions (CDF) were calculated based on the histogram distributions. Comparing these CDFs, the transformation function can be determined. Application of this transformation function not only improves the visual similarity of matching slices it can also be used for further quantitative analysis.
Original languageEnglish
Title of host publicationProceedings of SPIE Photonic Therapeutics and Diagnostics XII
EditorsBernard Choi, N. Kollias, H. Zeng, H. Wook Kang, B.J.F. Wong, J.F. Ilgner, G.J. Tearney, K.W. Gregory, L. Marcu, M.C. Skala, P.J. Campagnola, A. Mandelis, M.D. Morris
Place of PublicationBellingham
Number of pages7
ISBN (Print)9781628419245
Publication statusPublished - 2016
EventSPIE BIOS: Photonic Therapeutics and Diagnostics XII - San Francisco, United States
Duration: 13 Feb 201618 Feb 2016

Publication series

NameProceedings of SPIE


ConferenceSPIE BIOS
CountryUnited States
CitySan Francisco


  • intravascular optical coherence tomography
  • light intensity
  • histogram matching
  • intensity matching
  • St. Jude Medical Inc.
  • Terumo Corp

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