Metrics of green chemistry: Waste minimization

Roger A. Sheldon*, Moira L. Bode, Stephanie G. Akakios

*Corresponding author for this work

Research output: Contribution to journalReview articleScientificpeer-review

3 Citations (Scopus)


The increasingly apparent negative impact of human activities on the environment has heightened the urgency for the chemistry community to adopt greener and more sustainable practices. The E-factor can still be considered a valuable tool in this drive, particularly because of its broad acceptance and familiarity amongst both industrial and academic chemists. An important factor in broadening the adoption of green principles is ensuring that the academics responsible for training the next generation of chemists prioritise green and sustainable practices in their undergraduate and post graduate laboratories. Green metrics must be easy to use to motivate the broader chemistry community to develop greener syntheses. For maximum impact to be achieved the detail of the exact green metrics applied are less important than their adoption by the broader chemical community. Of growing importance is the replacement of fossil resources with renewable alternatives to reduce greenhouse gas emission that is a significant driver of climate change. The C factor is used to compare the carbon footprints of different routes to a particular product.

Original languageEnglish
Article number100569
Number of pages6
JournalCurrent Opinion in Green and Sustainable Chemistry
Publication statusPublished - 2022


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