Production of Co-58m in a siphon-style liquid target on a medical cyclotron

L. Mues genannt Koers, S. W. McNeil, V. Radchenko, E. Paulssen, C. Hoehr*

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

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We present the production of 58mCo on a small, 13 MeV medical cyclotron utilizing a siphon style liquid target system. Different concentrated iron(III)-nitrate solutions of natural isotopic distribution were irradiated at varying initial pressures and subsequently separated by solid phase extraction chromatography. The radio cobalt (58m/gCo and 56Co) was successfully produced with saturation activities of (0.35 ± 0.03) MBq μA−1 for 58mCo with a separation recovery of (75 ± 2) % of cobalt after one separation step utilizing LN-resin.

Original languageEnglish
Article number110734
Number of pages9
JournalApplied Radiation and Isotopes
Publication statusPublished - 2023

Bibliographical note

Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.


  • Cobalt-58m
  • Cyclotron production
  • Liquid target
  • Meitner-Auger therapy
  • Radiometal
  • Small medical cyclotron


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