RNA Processing and Export.

R.H Hocine; D Singer; D Grunwald

doi:doi:10.1101/cshperspect.a000752

RNA Processing and Export.

R.H Hocine, D Singer, D Grunwald

BN/David Grunwald Lab

Research output: Contribution to journal › Article › Scientific › peer-review

Abstract

doi:10.1101/cshperspect.a000752 Abstract Messenger RNAs undergo 5' capping, splicing, 3'-end processing, and export before translation in the cytoplasm. It has become clear that these mRNA processing events are tightly coupled and have a profound effect on the fate of the resulting transcript. This processing is represented by modifications of the pre-mRNA and loading of various protein factors. The sum of protein factors that stay with the mRNA as a result of processing is modified over the life of the transcript, conferring significant regulation to its expression.

Original language	English
Journal	Cold Spring Harbor Perspectives in Biology
Issue number	000752
DOIs	https://doi.org/doi:10.1101/cshperspect.a000752
Publication status	Published - 2010

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Peer-lijst tijdschrift

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title = "RNA Processing and Export.",

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AU - Singer, D

AU - Grunwald, D

PY - 2010

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N2 - doi:10.1101/cshperspect.a000752 Abstract Messenger RNAs undergo 5' capping, splicing, 3'-end processing, and export before translation in the cytoplasm. It has become clear that these mRNA processing events are tightly coupled and have a profound effect on the fate of the resulting transcript. This processing is represented by modifications of the pre-mRNA and loading of various protein factors. The sum of protein factors that stay with the mRNA as a result of processing is modified over the life of the transcript, conferring significant regulation to its expression.

AB - doi:10.1101/cshperspect.a000752 Abstract Messenger RNAs undergo 5' capping, splicing, 3'-end processing, and export before translation in the cytoplasm. It has become clear that these mRNA processing events are tightly coupled and have a profound effect on the fate of the resulting transcript. This processing is represented by modifications of the pre-mRNA and loading of various protein factors. The sum of protein factors that stay with the mRNA as a result of processing is modified over the life of the transcript, conferring significant regulation to its expression.

KW - Peer-lijst tijdschrift

U2 - doi:10.1101/cshperspect.a000752

DO - doi:10.1101/cshperspect.a000752

M3 - Article

SN - 1943-0264

JO - Cold Spring Harbor Perspectives in Biology

JF - Cold Spring Harbor Perspectives in Biology

IS - 000752

ER -

RNA Processing and Export.

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