RNA Processing and Export.

R.H Hocine, D Singer, D Grunwald

Research output: Contribution to journalArticleScientificpeer-review


doi:10.1101/cshperspect.a000752 Abstract Messenger RNAs undergo 5' capping, splicing, 3'-end processing, and export before translation in the cytoplasm. It has become clear that these mRNA processing events are tightly coupled and have a profound effect on the fate of the resulting transcript. This processing is represented by modifications of the pre-mRNA and loading of various protein factors. The sum of protein factors that stay with the mRNA as a result of processing is modified over the life of the transcript, conferring significant regulation to its expression.
Original languageEnglish
JournalCold Spring Harbor Perspectives in Biology
Issue number000752
Publication statusPublished - 2010


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